Drugs efficacy evaluations
and much more
OSTEOARTHRITIS BIOMARKERS
During the past years, a major step forward has been done in the clinical use of osteoarthritis biomarkers.
New measurement technologies have been developed and several biomarkers were identified.
New measurement technologies have been developed and several biomarkers were identified.
BIOCHEMICAL BIOMARKERS
FOR THE EVALUATION OF OSTEOARTHRITIS
FOR THE EVALUATION OF OSTEOARTHRITIS
- CTX-II
- C-Terminal telopeptide of collagen type II
- α-CTX-II
- Type II collagen α chains collagenase neoepitope
- PIINP
- Type II collagen propeptides
- C2C
- Type II collagen cleavage product
- C2M
- Collagen type II-specific neoepitope
- CTX-I, α-CTX-I
- C-terminal telopeptide of collagen type I
- PINP
- Aminoterminal propeptide of collagen type I
- C1,C2
- Types I and II collagen cleavage neoepitope
- Chondroitin sulfate epitope 846
- COMP & D-COMP
- Cartilage oligomeric matrix proteins
- FSTL-1
- Follistatin-like protein 1
- Hyaluronic Acid
- Hyaluronan
- MMP-1, MMP-3, MMP-9, MMP-13 and TIMPs
- Matrix metalloproteinases
- hs-CRP, IL-1β and IL-6
- Inflammatory biomarkers
- Adiponectin, Leptin
- Adipokines
- sOB-Rb
- Soluble receptor for leptin
- Periostin
- Cellular interactions in bone
- DKKs and SOST
- Wnt inhibitors
- Uric acid
Legend of abbreviations
- COMP
- Cartilage oligomeric protein
- COX-2
- Cyclo-oxygenase-2
- hs-CRP
- High sensitivity C reactive protein
- IL
- Interleukin
- MMP
- Matrix metalloproteinase
- PIINP
- N-propeptide II of type II collagen
- SOST
- Sclerostin
- TIMP
- Tissue inhibitor of matrix metalloproteinase