BIOMARKERS
CARES offers a large panel of biomarkers used to evaluate and monitor qualitative and quantitative changes in a wide range of therapeutic areas.
Abbreviation
Full name
Role
Analysis method
Abbreviation
uCuP-MGP dp-uc MGP
Full Name
Uncarboxylated unphsophorylated matrix-gla protein (uCuP-MGP)
Role
MGP is a vitamin K-dependent mineral-binding protein in the extra-cellular matrix. It is synthesized in vascular smooth muscle cells and chondrocytesx. MGP is a potent inhibitor of soft-tissue calcification through hydroxyapatite-absorption, and may thus potentially protect against arterial calcification.
Analysis Method
IDS Isys